![]() Thus, the current analysis of the Tarumizu population study indicated that the detection of uncontrolled hypertension is an important first step of the population approach. A recent prospective study, the CAVI-J study, demonstrated that a CAVI >9.5 is a predictor of stroke and heart failure in outpatients with cardiovascular risk. A systematic review assessing the association between CAVI and cardiovascular disease (9 prospective studies ( nā=ā5214) and 17 cross-sectional studies ( nā=ā7309)), with most studies enrolling populations at high risk of cardiovascular disease in Asia, demonstrated a modest association between the CAVI and incident cardiovascular disease risk. The CAVI is the measure of arterial stiffness that reflects the stiffness from the ascending aorta to the ankle arteries, demonstrates less dependence on BP during evaluation, and is associated with risk factors, organ damage, and cardiovascular events. In the Tarumizu population study, the uncontrolled hypertensive group exhibited a significantly higher prevalence of increased cardio-ankle vascular index (CAVI) scores, defined using the 9.0 pathological threshold, than the normal group (nonhypertensive individuals without medication), while there was no significant difference between the good BP control and normal BP groups. More recently, the hypertension societies of 14 Asian countries/regions agreed to provide future directions for overcoming hypertension in Asian populations. In 2022, the HOPE Asia Network released seven effective approaches and early morning hypertension practical treatment approaches for hypertension management in Asia and re-emphasized early morning home blood pressure as a quality index for hypertension management in Asia. ![]() The HOPE Asia Network, a group of volunteer hypertension experts from Asian countries, has been working to improve hypertension control in Asian countries, collecting evidence on various issues related to hypertension treatment in Asia. ![]() In particular, uncontrolled hypertension is more common in Asian countries, except in South Korea and Taiwan, although the benefit of strict BP control is greater for Asians than for westerners. Uncontrolled hypertension is the greatest challenge worldwide. A cross-sectional analysis of a community-based cohort study in Tarumizu demonstrated that patients with uncontrolled hypertension are associated with increased arterial stiffness compared with those without hypertension. ![]()
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